CD23 Expression in Mantle Cell Lymphoma: Clinicopathologic Features of 18 Cases
نویسندگان
چکیده
منابع مشابه
Clinicopathologic features of 112 cases with mantle cell lymphoma
OBJECTIVE This study aims to explore the clinicopathologic features of 112 patients with mantle cell lymphoma (MCL). METHODS Data from 112 MCL cases were collected, and immunohistochemical assay was conducted. Fluorescence in situ hybridization (FISH) detected a break in the CCND1 gene. The t-test was used in the statistical analysis. RESULTS All tumor cells in the 112 cases expressed B cel...
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Mantle cell lymphoma (MCL) accounts for approximately 6% of non-Hodgkin's lymphomas. Patients usually present with advanced disease, with a tendency for extranodal involvement. MCL is an aggressive lymphoma with moderate chemosensitivity, but it remains one of the most difficult therapeutic challenges. Complete response rates to chemotherapy range from 20% to 40%, with median survivals of 2 1/2...
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Mantle cell lymphoma (MCL) is a relatively uncommon yet distinct type of malignant lymphoma whose clinical and pathological characterization has been limited by the small numbers of cases published to date. We studied 80 cases of MCL seen at a single institution over 7 years to determine both clinical and pathological prognostic factors. The patients in this study were predominantly male (70%) ...
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Working Formulation (WF), which has been used extensively in the United States and served as a common language to translate between six different classification schemes, failed to recognize MCL as a distinct entity. In the WF, MCL is classified as diffuse small cleaved most frequently, but also as follicular, small cleaved cell type, small lymphocytic lymphoma, diffuse large cell type and lymho...
متن کاملCD10-positive mantle cell lymphoma: clinicopathologic and prognostic study of 30 cases
Mantle cell lymphoma is usually negative for CD10 which is useful in distinguishing MCL from other CD10 + B cell lymphomas. Here we assessed the clinicopathologic features of 30 cases of CD10+ MCL, the largest series to date in the English literature, and compared them with a group of 212 typical MCL cases (CD5+, CD10-negative, CD23-negative, cyclin D1+). The 30 patients with CD10+ MCL included...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2003
ISSN: 0002-9173
DOI: 10.1309/xv4a-g7em-wqu7-er67